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Symbol
Name
ID

Spp1
secreted phosphoprotein 1
MGI:98389

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Anorexia	Hypopituitarism	Spinal cord compression	Seizure	Paresthesia
Disease(s) Associated with SPP1	Anorexia	Hypopituitarism	Spinal cord compression	Seizure	Paresthesia
biliary atresia
multiple myeloma
pancreatic cancer

Mouse Phenotypes		nervous system phenotype	decreased susceptibility to dopaminergic neuron neurotoxicity	abnormal microglial cell morphology	abnormal substantia nigra morphology	abnormal striatum morphology	increased neuron number
Availability	Mouse Genotype	nervous system phenotype		abnormal microglial cell morphology	abnormal substantia nigra morphology	abnormal striatum morphology	increased neuron number
	Spp1^tm1Blh/Spp1^tm1Blh
	Spp1^tm1Rit/Spp1^tm1Rit	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23